GRAP anticorps (AA 128-217)

N° du produit ABIN7267510

Cet anticorps Lapin Polyclonal détecte spécifiquement GRAP dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour GRAP anticorps (AA 128-217) (ABIN7267510)

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRAP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRAP anticorps

Épitope: AA 128-217

Fonction: GRAP Rabbit pAb

Séquence: LNELVDFYRT TTIAKKRQIF LRDEEPLLKS PGACFAQAQF DFSAQDPSQL SFRRGDIIEV LERPDPHWWR GRSCGRVGFF PRSYVQPVHL

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 128-217 of human GRAP (NP_006604.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GRAP

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Autre désignation: GRAP

Sujet: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.,GRAP,Signal Transduction,G protein signaling,Signal Transduction,GRAP

Poids moléculaire: 25kDa

ID gène: 10750

UniProt: Q13588