K-RAS anticorps (pSer89)

N° du produit ABIN7267530

Cet anticorps anti-K-RAS est un anticorps Lapin Polyclonal détectant K-RAS dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour K-RAS anticorps (pSer89) (ABIN7267530)

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp K-RAS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-K-RAS anticorps

Épitope: pSer89

Fonction: Phospho-KRAS-S89 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S89 of human KRAS.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur K-RAS

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS

Sujet: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2, c-Ki-ras2, GTPase KRas,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,Kinase,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cytoskeleton,Actins,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,Cardiovascular,Angiogenesis,KRAS

Poids moléculaire: 21kDa

ID gène: 3845

UniProt: P01116