ChT anticorps (AA 421-580)

N° du produit ABIN7267643

Détail du produit anti-ChT anticorps

Antigène: ChT (High Affinity Choline Transporter (ChT))

Épitope: AA 421-580

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ChT est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: SLC5A7 Rabbit pAb

Séquence: LLCVLFVKGT NTYGAVAGYV SGLFLRITGG EPYLYLQPLI FYPGYYPDDN GIYNQKFPFK TLAMVTSFLT NICISYLAKY LFESGTLPPK LDVFDAVVAR HSEENMDKTI LVKNENIKLD ELALVKPRQS MTLSSTFTNK EAFLDVDSSP EGSGTEDNLQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 421-580 of human SLC5A7 (NP_068587.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ChT

Antigène: ChT (High Affinity Choline Transporter (ChT))

Autre désignation: SLC5A7 (ChT Produits)

Synonymes: anticorps CHT, anticorps CHT1, anticorps HMN7A, anticorps hCHT, anticorps Cht1, anticorps solute carrier family 5 member 7, anticorps solute carrier family 5 (choline transporter), member 7, anticorps SLC5A7, anticorps Slc5a7

Sujet: This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.,SLC5A7,CHT,CHT1,CMS20,HMN7A,Signal Transduction,Endocrine & Metabolism,Neuroscience,SLC5A7

Poids moléculaire: 63kDa

ID gène: 60482

UniProt: Q9GZV3