IDO1 anticorps
Aperçu rapide pour IDO1 anticorps (ABIN7267863)
Antigène
Voir toutes IDO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- IDO1 Rabbit mAb
-
Réactivité croisée
- Humain, Souris
-
Attributs du produit
- Monoclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- A synthesized peptide derived from human IDO1
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
-
Autre désignation
- IDO1
-
Sujet
- This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011],IDO, IDO-1, INDO,Amino acid metabolism,Cancer,Cardiovascular,Endocrine & Metabolism,Immunology & Inflammation,Signal Transduction,IDO1
-
Poids moléculaire
- 45kDa
-
ID gène
- 3620
-
UniProt
- P14902
-
Pathways
- Activated T Cell Proliferation
Antigène
-