Integrin beta 4 anticorps

N° du produit ABIN7267931

L’anticorps anti-Integrin beta 4 Monoclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de Integrin beta 4 dans des échantillons provenant de Humain. }

Aperçu rapide pour Integrin beta 4 anticorps (ABIN7267931)

Antigène: Integrin beta 4 (ITGB4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Integrin beta 4 anticorps

Fonction: Integrin beta 4 (ITGB4/CD104) Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Integrin beta 4 (ITGB4/CD104) (ITGB4/CD104)

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Integrin beta 4

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: ITGB4

Sujet: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],CD104, GP150,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,ITGB4

Poids moléculaire: 210kDa

ID gène: 3691

UniProt: P16144

Pathways: Integrin Complex