IDH3A anticorps (AA 28-366)
Aperçu rapide pour IDH3A anticorps (AA 28-366) (ABIN7268029)
Antigène
Voir toutes IDH3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 28-366
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Fonction
- IDH3A Rabbit pAb
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Séquence
- TGGVQTVTLI PGDGIGPEIS AAVMKIFDAA KAPIQWEERN VTAIQGPGGK WMIPSEAKES MDKNKMGLKG PLKTPIAAGH PSMNLLLRKT FDLYANVRPC VSIEGYKTPY TDVNIVTIRE NTEGEYSGIE HVIVDGVVQS IKLITEGASK RIAEFAFEYA RNNHRSNVTA VHKANIMRMS DGLFLQKCRE VAESCKDIKF NEMYLDTVCL NMVQDPSQFD VLVMPNLYGD ILSDLCAGLI GGLGVTPSGN IGANGVAIFE SVHGTAPDIA GKDMANPTAL LLSAVMMLRH MGLFDHAARI EAACFATIKD GKSLTKDLGG NAKCSDFTEE ICRRVKDLD
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 28-366 of human IDH3A (NP_005521.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
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Autre désignation
- IDH3A
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Sujet
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.,IDH3A,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,IDH3A
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Poids moléculaire
- 31kDa/40kDa
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ID gène
- 3419
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UniProt
- P50213
Antigène
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