KIF7 anticorps (AA 1044-1343)
Aperçu rapide pour KIF7 anticorps (AA 1044-1343) (ABIN7268137)
Antigène
Voir toutes KIF7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1044-1343
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Fonction
- KIF7 Rabbit pAb
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Séquence
- QLDEAIEALD AAIEYKNEAI TCRQRVLRAS ASLLSQCEMN LMAKLSYLSS SETRALLCKY FDKVVTLREE QHQQQIAFSE LEMQLEEQQR LVYWLEVALE RQRLEMDRQL TLQQKEHEQN MQLLLQQSRD HLGEGLADSR RQYEARIQAL EKELGRYMWI NQELKQKLGG VNAVGHSRGG EKRSLCSEGR QAPGNEDELH LAPELLWLSP LTEGAPRTRE ETRDLVHAPL PLTWKRSSLC GEEQGSPEEL RQREAAEPLV GRVLPVGEAG LPWNFGPLSK PRRELRRASP GMIDVRKNPL
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- KIF7 (Kinesin Family Member 7 (KIF7))
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Autre désignation
- KIF7
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Sujet
- This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.,KIF7,ACLS,AGBK,HLS2,JBTS12,UNQ340,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Hedgehog Signaling Pathway,Stem Cells,KIF7
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Poids moléculaire
- 150kDa
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ID gène
- 374654
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UniProt
- Q2M1P5
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Pathways
- Signalisation Hedgehog
Antigène
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