LGMN anticorps

N° du produit ABIN7268208

Cet anticorps anti-LGMN est un anticorps Lapin Monoclonal détectant LGMN dans WB. Adapté pour Humain.

Aperçu rapide pour LGMN anticorps (ABIN7268208)

Antigène: LGMN (Legumain (LGMN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LGMN est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LGMN anticorps

Fonction: Legumain (LGMN) Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Legumain (LGMN) (LGMN)

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LGMN

Antigène: LGMN (Legumain (LGMN))

Autre désignation: LGMN

Sujet: This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008],AEP, LGMN1, PRSC1,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Extracellular Matrix,Extracellular Matrix_Bone,Immunology & Inflammation,Signal Transduction,Ubiquitin,LGMN

Poids moléculaire: 36,57kDa

ID gène: 5641

UniProt: Q99538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades