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LIN28B anticorps

L’anticorps Lapin Monoclonal anti-LIN28B a été validé pour WB et IHC. Il convient pour détecter LIN28B dans des échantillons de Humain.
N° du produit ABIN7268267

Aperçu rapide pour LIN28B anticorps (ABIN7268267)

Antigène

Voir toutes LIN28B Anticorps
LIN28B (Lin-28 Homolog B (LIN28B))

Reactivité

  • 49
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 48
  • 1
  • 1
Lapin

Clonalité

  • 48
  • 2
Monoclonal

Conjugué

  • 34
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp LIN28B est non-conjugé

Application

  • 35
  • 22
  • 22
  • 18
  • 17
  • 6
  • 6
  • 4
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Fonction

    LIN28B Rabbit mAb

     Réactivité croisée

    Humain

    Attributs du produit

    Monoclonal Antibodies

    Purification

    Affinity purification

    Immunogène

    A synthesized peptide derived from human LIN28B

    Isotype

    IgG
  • Indications d'application

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    LIN28B (Lin-28 Homolog B (LIN28B))

    Autre désignation

    LIN28B

    Sujet

    The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012],CSDD2,Cancer,Epigenetics & Nuclear Signaling,Tumor biomarkers,LIN28B

    Poids moléculaire

    32kDa

    ID gène

    389421

    UniProt

    Q6ZN17
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