Lipin 1 anticorps
Aperçu rapide pour Lipin 1 anticorps (ABIN7268281)
Antigène
Voir toutes Lipin 1 (LPIN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Lipin 1 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human Lipin 1
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Lipin 1 (LPIN1)
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Autre désignation
- LPIN1
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Sujet
- This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017],PAP1,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Heart disease,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Diabetes,Heart,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Signal Transduction,LPIN1
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Poids moléculaire
- 130kDa
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ID gène
- 23175
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UniProt
- Q14693
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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