LRP6 anticorps (AA 20-150)

N° du produit ABIN7268299

Cet anticorps Lapin Polyclonal détecte spécifiquement LRP6 dans IF. Il présente une réactivité envers Humain.

Aperçu rapide pour LRP6 anticorps (AA 20-150) (ABIN7268299)

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP6 est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-LRP6 anticorps

Épitope: AA 20-150

Fonction: LRP6 Rabbit pAb

Séquence: APLLLYANRR DLRLVDATNG KENATIVVGG LEDAAAVDFV FSHGLIYWSD VSEEAIKRTE FNKTESVQNV VVSGLLSPDG LACDWLGEKL YWTDSETNRI EVSNLDGSLR KVLFWQELDQ PRAIALDPSS G

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human LRP6 (NP_002327.2).

Isotype: IgG

Information d'application

Indications d'application: IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LRP6

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6

Sujet: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.,LRP6,ADCAD2,STHAG7,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Microtubules,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,LRP6

Poids moléculaire: 180kDa

ID gène: 4040

UniProt: O75581

Pathways: Signalisation WNT, Tube Formation