MMP2 anticorps

N° du produit ABIN7268428

Cet anticorps Lapin Monoclonal détecte spécifiquement MMP2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MMP2 anticorps (ABIN7268428)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MMP2 anticorps

Fonction: MMP2 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human MMP2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2

Sujet: This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014],CLG4,CLG4A,MMP-2,MMP-II,MONA,TBE-1,MMP2,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Extracellular Matrix,Extracellular Matrix_MMPs,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Hypoxia,Invasion and Metastasis,Signal Transduction,Tumor biomarkers,Ubiquitin,MMP2

Poids moléculaire: 72kDa

ID gène: 4313

UniProt: P08253

Pathways: Activation of Innate immune Response