METAP2 anticorps

N° du produit ABIN7268490

Cet anticorps anti-METAP2 est un anticorps Lapin Monoclonal détectant METAP2 dans WB. Adapté pour Humain.

Aperçu rapide pour METAP2 anticorps (ABIN7268490)

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp METAP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-METAP2 anticorps

Fonction: METAP2 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human METAP2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur METAP2

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Autre désignation: METAP2

Sujet: The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],MAP2, MNPEP, p67eIF2,Amino acid metabolism,Cancer,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,METAP2

Poids moléculaire: 67kDa

ID gène: 10988

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling