Neuregulin 3 anticorps

N° du produit ABIN7268859

Détail du produit anti-Neuregulin 3 anticorps

Antigène: Neuregulin 3 (NRG3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuregulin 3 est non-conjugé

Application: Western Blotting (WB)

Fonction: Neuregulin-3 (NRG3) Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Neuregulin-3 (Neuregulin-3 (NRG3))

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Neuregulin 3

Antigène: Neuregulin 3 (NRG3)

Autre désignation: NRG3 (NRG3 Produits)

Synonymes: anticorps NRG3, anticorps HRG3, anticorps pro-NRG3, anticorps ska, anticorps RGD1559678, anticorps neuregulin 3, anticorps pro-neuregulin-3, membrane-bound isoform, anticorps NRG3, anticorps nrg3, anticorps LOC100478170, anticorps Nrg3

Sujet: This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009],HRG3, pro-NRG3,Cancer,ErbB-HER Signaling Pathway,Neuroscience,Signal Transduction,NRG3

Poids moléculaire: 56kDa

ID gène: 10718

UniProt: P56975

Pathways: Signalisation RTK