PAK7 anticorps (AA 600-700)
Aperçu rapide pour PAK7 anticorps (AA 600-700) (ABIN7269143)
Antigène
Voir toutes PAK7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 600-700
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Fonction
- PAK5 Rabbit pAb
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Séquence
- RKSLVGTPYW MAPEVISRLP YGTEVDIWSL GIMVIEMIDG EPPYFNEPPL QAMRRIRDSL PPRVKDLHKV SSVLRGFLDL MLVREPSQRA TAQELLGHPF L
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 600-700 of human PAK5 (NP_065074.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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Autre désignation
- PAK5
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Sujet
- The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.,PAK5,PAK7,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,TGF-b-Smad Signaling Pathway,Neuroscience,PAK5
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Poids moléculaire
- 80kDa
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ID gène
- 57144
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UniProt
- Q9P286
Antigène
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