PHKA1 anticorps (AA 600-820)

N° du produit ABIN7269367

Cet anticorps Lapin Polyclonal détecte spécifiquement PHKA1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PHKA1 anticorps (AA 600-820) (ABIN7269367)

Antigène: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHKA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PHKA1 anticorps

Épitope: AA 600-820

Fonction: PHKA1 Rabbit pAb

Séquence: QTGKLSEFLT TSCCTHLSFM DPGPEGKLYS EDYDDNYDYL ESGNWMNDYD STSHARCGDE VARYLDHLLA HTAPHPKLAP TSQKGGLDRF QAAVQTTCDL MSLVTKAKEL HVQNVHMYLP TKLFQASRPS FNLLDSPHPR QENQVPSVRV EIHLPRDQSG EVDFKALVLQ LKETSSLQEQ ADILYMLYTM KGPDWNTELY NERSATVREL LTELYGKVGE I

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human PHKA1 (NP_001116142.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PHKA1

Antigène: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Autre désignation: PHKA1

Sujet: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.,PHKA1,PHKA,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Calcium Signaling,PHKA1

Poids moléculaire: 129kDa/135kDa/137kDa

ID gène: 5255

UniProt: P46020

Pathways: Cellular Glucan Metabolic Process