PCBP1 anticorps

N° du produit ABIN7269448

Cet anticorps Lapin Monoclonal détecte spécifiquement PCBP1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PCBP1 anticorps (ABIN7269448)

Antigène: PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PCBP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCBP1 anticorps

Fonction: hnRNP E1/PCBP1 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human hnRNP E1/hnRNP E1/PCBP1.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PCBP1

Antigène: PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Autre désignation: PCBP1

Sujet: This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.,PCBP1; HEL-S-85; HNRPE1; HNRPX; hnRNP-E1; hnRNP-X; poly(rC)-binding protein 1,Epigenetics & Nuclear Signaling,RNA Binding,,PCBP1

Poids moléculaire: 40kDa

ID gène: 5093

UniProt: Q15365