PRKAB1 anticorps

N° du produit ABIN7269654

Cet anticorps anti-PRKAB1 Monoclonal Lapin (ABIN7269654) détecte spécifiquement PRKAB1 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PRKAB1 anticorps (ABIN7269654)

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PRKAB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PRKAB1 anticorps

Fonction: AMPKβ1 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human AMPKbeta1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRKAB1

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Autre désignation: PRKAB1

Sujet: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008],AMPK, HAMPKb,AMPK Signaling Pathway,Autophagy,Autophagy_Regulator,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Kinase,Kinase_Serine/threonine kinases,Lipid Metabolism,Lipids,Lipids_Fatty Acids,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Regulator of mTOR complex function,Protein phosphorylation,Signal Transduction,Warburg Effect,PRKAB1

Poids moléculaire: 38kDa

ID gène: 5564

UniProt: Q9Y478

Pathways: AMPK Signaling, L'effet Warburg