RAD50 anticorps

N° du produit ABIN7269826

Cet anticorps Lapin Monoclonal détecte spécifiquement RAD50 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour RAD50 anticorps (ABIN7269826)

Antigène: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD50 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAD50 anticorps

Fonction: Rad50 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Rad50

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD50

Antigène: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Autre désignation: RAD50

Sujet: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],NBSLD, RAD502, hRad50,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,RAD50

Poids moléculaire: 154kDa

ID gène: 10111

UniProt: Q92878

Pathways: Réparation de l'ADN, Protein targeting to Nucleus