RNASEH2A anticorps (AA 1-299)

N° du produit ABIN7269981

Détail du produit anti-RNASEH2A anticorps

Antigène: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Épitope: AA 1-299

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNASEH2A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: RNASEH2A Rabbit pAb

Séquence: MDLSELERDN TGRCRLSSPV PAVCRKEPCV LGVDEAGRGP VLGPMVYAIC YCPLPRLADL EALKVADSKT LLESERERLF AKMEDTDFVG WALDVLSPNL ISTSMLGRVK YNLNSLSHDT ATGLIQYALD QGVNVTQVFV DTVGMPETYQ ARLQQSFPGI EVTVKAKADA LYPVVSAASI CAKVARDQAV KKWQFVEKLQ DLDTDYGSGY PNDPKTKAWL KEHVEPVFGF PQFVRFSWRT AQTILEKEAE DVIWEDSASE NQEGLRKITS YFLNEGSQAR PRSSHRYFLE RGLESATSL

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_006388.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNASEH2A

Antigène: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Autre désignation: RNASEH2A (RNASEH2A Produits)

Synonymes: anticorps 2400006P09Rik, anticorps RNASEHI, anticorps RNHIA, anticorps RNHL, anticorps zgc:56307, anticorps AGS4, anticorps JUNB, anticorps ribonuclease H2 subunit A, anticorps ribonuclease H2, large subunit, anticorps ribonuclease H2, subunit A, anticorps ribonuclease H2 subunit A L homeolog, anticorps rnaseh2a, anticorps RNASEH2A, anticorps Rnaseh2a, anticorps rnaseh2a.L

Sujet: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.,RNASEH2A,AGS4,JUNB,RNASEHI,RNHIA,RNHL,Epigenetics & Nuclear Signaling,RNASEH2A

Poids moléculaire: 33kDa

ID gène: 10535

UniProt: O75792