STAU1/Staufen anticorps

N° du produit ABIN7270586

L’anticorps anti-STAU1/Staufen Monoclonal Lapin est utilisé pour la détection de STAU1/Staufen dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour STAU1/Staufen anticorps (ABIN7270586)

Antigène: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp STAU1/Staufen est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STAU1/Staufen anticorps

Fonction: Staufen Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Staufen

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur STAU1/Staufen

Antigène: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Autre désignation: STAU1

Sujet: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008],PPP1R150, STAU,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microtubules,Neuroscience,Signal Transduction,STAU1

Poids moléculaire: 55kDa

ID gène: 6780

UniProt: O95793

Pathways: Asymmetric Protein Localization