SNAP23 anticorps (AA 1-211)
Aperçu rapide pour SNAP23 anticorps (AA 1-211) (ABIN7270670)
Antigène
Voir toutes SNAP23 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-211
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Fonction
- SNAP23 Rabbit pAb
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Séquence
- MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE QLNRIEEGLD QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG PVTNGQLQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ NPQIKRITDK ADTNRDRIDI ANARAKKLID S
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human SNAP23 (NP_003816.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
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Autre désignation
- SNAP23
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Sujet
- Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.,SNAP23,HsT17016,SNAP-23,SNAP23A,SNAP23B,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,SNAP23
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Poids moléculaire
- 17kDa/23kDa
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ID gène
- 8773
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UniProt
- O00161
Antigène
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