TARDBP anticorps

N° du produit ABIN7270730

L’anticorps Lapin Monoclonal anti-TARDBP a été validé pour WB, IHC et IF. Il convient pour détecter TARDBP dans des échantillons de Humain.

Aperçu rapide pour TARDBP anticorps (ABIN7270730)

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TARDBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TARDBP anticorps

Fonction: TDP-43/TARDB Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human TDP-43/TARDB

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TARDBP

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Autre désignation: TARDBP

Sujet: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],ALS10,TDP-43,TARDBP,TDP43,Apoptosis,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Amyotrophic lateral sclerosis,ALS,Neuroscience,Other Neurological disorders,RNA Binding,TARDBP

Poids moléculaire: 45kDa

ID gène: 23435

UniProt: Q13148

Pathways: Positive Regulation of Peptide Hormone Secretion