TLR6 anticorps (AA 32-200)
Aperçu rapide pour TLR6 anticorps (AA 32-200) (ABIN7270847)
Antigène
Voir toutes TLR6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 32-200
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Fonction
- TLR6 Rabbit pAb
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Séquence
- NEFAVDKSKR GLIHVPKDLP LKTKVLDMSQ NYIAELQVSD MSFLSELTVL RLSHNRIQLL DLSVFKFNQD LEYLDLSHNQ LQKISCHPIV SFRHLDLSFN DFKALPICKE FGNLSQLNFL GLSAMKLQKL DLLPIAHLHL SYILLDLRNY YIKENETESL QILNAKTLH
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 32-200 of human TLR6 (NP_006059.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TLR6 (Toll-Like Receptor 6 (TLR6))
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Autre désignation
- TLR6
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Sujet
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.,TLR6,CD286,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TLR6
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Poids moléculaire
- 55kDa/91kDa
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ID gène
- 10333
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UniProt
- Q9Y2C9
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
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