TRIM5 anticorps (AA 100-200)

N° du produit ABIN7270992

Détail du produit anti-TRIM5 anticorps

Antigène: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Épitope: AA 100-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM5 est non-conjugé

Application: Western Blotting (WB)

Fonction: TRIM5 Rabbit pAb

Séquence: EKLLLFCQED GKVICWLCER SQEHRGHHTF LTEEVAREYQ VKLQAALEML RQKQQEAEEL EADIREEKAS WKTQIQYDKT NVLADFEQLR DILDWEESNE L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TRIM5 (NP_149083.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TRIM5

Antigène: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Autre désignation: TRIM5 (TRIM5 Produits)

Synonymes: anticorps TRIM5, anticorps RNF88, anticorps TRIM5alpha, anticorps EG667823, anticorps Gm8833, anticorps RGD1304579, anticorps tripartite motif containing 5, anticorps tripartite motif-containing 5, anticorps TRIM5, anticorps Trim5

Sujet: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.,TRIM5,RNF88,TRIM5alpha,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Immunology & Inflammation,TRIM5

Poids moléculaire: 29kDa/31kDa/37kDa/40kDa/46kDa/56kDa

ID gène: 85363

UniProt: Q9C035

Pathways: Activation of Innate immune Response