XIAP anticorps

N° du produit ABIN7271400

Cet anticorps anti-XIAP est un anticorps Lapin Monoclonal détectant XIAP dans WB. Adapté pour Humain.

Aperçu rapide pour XIAP anticorps (ABIN7271400)

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp XIAP est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: KO Validated

Détail du produit anti-XIAP anticorps

Fonction: [KO Validated] XIAP Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human XIAP.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur XIAP

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Autre désignation: XIAP

Sujet: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.,XIAP,API3,BIRC4,IAP-3,ILP1,MIHA,XLP2,hIAP-3,hIAP3,Cancer,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Death receptors & ligands,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,XIAP

Poids moléculaire: 56kDa

ID gène: 331

UniProt: P98170

Pathways: Apoptose, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis