YTHDC2 anticorps (AA 105-1231)
Aperçu rapide pour YTHDC2 anticorps (AA 105-1231) (ABIN7599661)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 105-1231
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Fonction
- Anti-YTHDC2 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-YTHDC2 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human YTHDC2 recombinant protein (Position: K105-K1231).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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Autre désignation
- YTHDC2
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Sujet
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Background: YTH domain containing 2 is a protein that in humans is encoded by the YTHDC2 gene. This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
Gene Full Name: YTH N6-methyladenosine RNA binding protein C2
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Poids moléculaire
- 175 kDa
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ID gène
- 64848
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UniProt
- Q9H6S0
Antigène
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