CCR2 anticorps
Aperçu rapide pour CCR2 anticorps (ABIN7271871)
Antigène
Voir toutes CCR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD192 Unconjugated Antibody
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Attributs du produit
- The clone 1D9, a mouse monoclonal antibody selectively recognizes C-C chemokine receptor type 2 (CCR2), a cell surface protein known as CD192. It belongs to the beta chemokine receptor family having seven transmembrane (7-TM) G protein-linked receptors. CD192 interacts with its ligands CCL2, CCL8 and CCL16. It is expressed on basophils, monocytes/macrophages, dendritic cells, activated T cells and B cells. CD192 plays an important role in the monocytic infiltration of tissues associated with diseases including atherosclerosis, rheumatoid arthritis, and tumors.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- CCR2 transfected human cell line
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Autre désignation
- CD192
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ID gène
- 729230
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UniProt
- P41597
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Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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