SARS-CoV-2 Spike S1 anticorps (RBD)

N° du produit ABIN7383757

Cet anticorps anti-SARS-CoV-2 Spike S1 est un anticorps Lapin Monoclonal détectant SARS-CoV-2 Spike S1 dans ELISA et IF. Adapté pour SARS Coronavirus-2 (SARS-CoV-2).

Aperçu rapide pour SARS-CoV-2 Spike S1 anticorps (RBD) (ABIN7383757)

Antigène: SARS-CoV-2 Spike S1

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SARS-CoV-2 Spike S1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Clone: R007

Détail du produit anti-SARS-CoV-2 Spike S1 anticorps

Épitope: RBD

Specificité: SARS-COV-2 Spike S1 Monoclonal Antibody(2019-nCoV)

Purification: Protein A affinity purification

Immunogène: Recombinant 2019-nCoV Spike/RBD Protein (RBD),PKSR030507

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1:5,000-1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 0.2 μm filtered solution in PBS

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SARS-CoV-2 Spike S1

Antigène: SARS-CoV-2 Spike S1

Classe de substances: Viral Protein

Sujet: Coronavirus s1,coronavirus s2,coronavirus spike,cov spike,ncov RBD,ncov s1,ncov s2,ncov spike,novel coronavirus RBD,novel coronavirus s1,novel coronavirus s2,novel coronavirus spike,RBD,S1,s2,Spike RBD,Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.