AGXT anticorps

N° du produit ABIN7384024

Cet anticorps anti-AGXT est un anticorps Lapin Polyclonal détectant AGXT dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour AGXT anticorps (ABIN7384024)

Antigène: AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGXT est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-AGXT anticorps

Purification: Affinity purification

Immunogène: Synthetic peptide of human AGXT

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur AGXT

Antigène: AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

Autre désignation: AGXT

Sujet: AGT,AGT1,Agxt,AGXT1,Alanine glyoxylate aminotransferase,Alanine glyoxylate aminotransferase3,Alanine--glyoxylate aminotransferase,EC 2.6.1.44,EC 2.6.1.51,Hepatic peroxisomal alanine glyoxylate aminotransferase,Hepatic peroxisomal alanine:glyoxylate aminotransferase,L alanine glyoxylate aminotransferase 1,MS773,PH1,Serine pyruvate aminotransferase,Serine--pyruvate aminotransferase,Serine--pyruvate aminotransferase,mitochondrial,Serine:pyruvate aminotransferase,SPAT,SPT,SPYA,TLH6,Serine-pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

Poids moléculaire: 43 kDa

NCBI Accession: NP_000021

UniProt: P21549

Pathways: Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport