Lactate Dehydrogenase A anticorps

N° du produit ABIN7384336

Cet anticorps anti-Lactate Dehydrogenase A est un anticorps Lapin Monoclonal détectant Lactate Dehydrogenase A dans WB. Adapté pour Humain et Rat.

Aperçu rapide pour Lactate Dehydrogenase A anticorps (ABIN7384336)

Antigène: Lactate Dehydrogenase A (LDHA)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Lactate Dehydrogenase A est non-conjugé

Application: Western Blotting (WB)

Clone: R09-9A7

Détail du produit anti-Lactate Dehydrogenase A anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Lactate Dehydrogenase A

Antigène: Lactate Dehydrogenase A (LDHA)

Autre désignation: Lactate Dehydrogenase A

Sujet: Cell proliferation-inducing gene 19 protein,GSD11,L lactate dehydrogenase A chain,l7R2,LDH M,LDH muscle subunit,LDH1,PIG19 Proliferation-inducing gene 19,LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Poids moléculaire:

Observed_MW: 37kDa

Calculated_MW: 37kDa

ID gène: 3939

UniProt: P00338

Pathways: L'effet Warburg