SF3B1 anticorps

N° du produit ABIN7384395

L’anticorps Lapin Monoclonal anti-SF3B1 a été validé pour WB et IHC (p). Il convient pour détecter SF3B1 dans des échantillons de Humain, Souris et Hamster.

Aperçu rapide pour SF3B1 anticorps (ABIN7384395)

Antigène: SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Reactivité: Humain, Souris, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SF3B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R08-6I2

Détail du produit anti-SF3B1 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SF3B1

Antigène: SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Autre désignation: SF3B1

Sujet: SF3B1,Hsh155,MDS,PRP10,PRPF10,SAP155,SF3b155,This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 146kDa

Calculated_MW: 146kDa

ID gène: 23451

UniProt: O75533

Pathways: Chromatin Binding