APC anticorps

N° du produit ABIN7384414

Cet anticorps anti-APC est un anticorps Lapin Monoclonal détectant APC dans WB. Adapté pour Humain.

Aperçu rapide pour APC anticorps (ABIN7384414)

Antigène: APC (Adenomatous Polyposis Coli (APC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp APC est non-conjugé

Application: Western Blotting (WB)

Clone: R06-2E4

Détail du produit anti-APC anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APC

Antigène: APC (Adenomatous Polyposis Coli (APC))

Autre désignation: APC

Sujet: Adenomatous Polyposis Coli,Adenomatous polyposis coli protein,Apc,APC,CC1,Deleted in polyposis 2.5,DP2,DP2.5,DP3,FAP,FPC,GS,Protein APC,This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Poids moléculaire:

Observed_MW: 160kDa

Calculated_MW: 312kDa

ID gène: 324

UniProt: P25054

Pathways: Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization