IMPDH2 anticorps

N° du produit ABIN7384457

Cet anticorps Lapin Monoclonal détecte spécifiquement IMPDH2 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IMPDH2 anticorps (ABIN7384457)

Antigène: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IMPDH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R06-1B8

Détail du produit anti-IMPDH2 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IMPDH2

Antigène: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Autre désignation: IMPDH2

Sujet: IMDH2,IMP (inosine monophosphate) dehydrogenase 2,IMP dehydrogenase 2,IMP oxireductase 2,IMPD 2,IMPD2,IMPDH 2,IMPDH II,IMPDH-II,Impdh2,Inosine 5' monophosphate dehydrogenase 2,Inosine 5' phosphate dehydrogenase 2,Inosine monophosphate dehydrogenase type II,Inosine-5''-monophosphate dehydrogenase 2,This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Poids moléculaire:

Observed_MW: 56kDa

Calculated_MW: 56kDa

ID gène: 3615

UniProt: P12268

Pathways: Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome