DDB1 anticorps (C-Term)

N° du produit ABIN7448511

Cet anticorps anti-DDB1 est un anticorps Lapin Polyclonal détectant DDB1 dans IHC. Adapté pour Humain et Souris.

Aperçu rapide pour DDB1 anticorps (C-Term) (ABIN7448511)

Antigène: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDB1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-DDB1 anticorps

Épitope: C-Term

Fonction: Rabbit anti-DDB1 IHC Antibody, Affinity Purified

Homologie: Rat,X. laevis,X. tropicalis,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Chinese hamster,Small-eared galago,Gray short-tailed opossum,Green monkey,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Naked mole rat,African elephant,White-tufted-ear marmoset,Tasmanian devil,Little brown bat

Purification: Affinity Purified

Immunogène: Between AA 1100 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DDB1

Antigène: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Autre désignation: DDB1

Sujet: Background: DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.

ID gène: 1642

UniProt: Q16531, Q13289

Pathways: Réparation de l'ADN