INPPL1 anticorps (AA 100-150)

N° du produit ABIN7448605

Cet anticorps Lapin Polyclonal détecte spécifiquement INPPL1 dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour INPPL1 anticorps (AA 100-150) (ABIN7448605)

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INPPL1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-INPPL1 anticorps

Épitope: AA 100-150

Fonction: Rabbit anti-INPPL1/SHIP2 IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Rabbit,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Chinese hamster,Naked mole rat,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 100 and 150

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur INPPL1

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Autre désignation: INPPL1/SHIP2

Sujet: Background: INPPL1 (Inositol Polyphosphate Phosphatase-Like Protein 1) is a phosphatidylinositol phosphatase that negatively regulates phosphoinositide 3-kinase (PI3K) pathways related to numerous cell activities. INPPL1 plays a role in PI3K-dependent insulin, macrophage colony-stimulating factor, and EGF signaling. INPPL1 is also involved in actin cytoskeletal remodeling, actin dynamics, and neuritogenesis. INPPL1 interacts with SHC1 (src-homology domain) to mediate EGFR signaling.

ID gène: 3636

NCBI Accession: NP_001558

UniProt: O15357

Pathways: Platelet-derived growth Factor Receptor Signaling