KDM5B anticorps (AA 1494-1544)

N° du produit ABIN7448613

Cet anticorps anti-KDM5B est un anticorps Lapin Polyclonal détectant KDM5B dans IHC. Adapté pour Humain.

Aperçu rapide pour KDM5B anticorps (AA 1494-1544) (ABIN7448613)

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM5B est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-KDM5B anticorps

Épitope: AA 1494-1544

Fonction: Rabbit anti-JARID1B IHC Antibody, Affinity Purified

Homologie: Mouse,Dog,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Small-eared galago,Northern white-cheeked gibbon,White-tufted-ear marmoset,African elephant

Purification: Affinity Purified

Immunogène: Between AA 1494 and 1544

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KDM5B

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Autre désignation: JARID1B

Sujet: Background: JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer.

ID gène: 10765

NCBI Accession: NP_006609

UniProt: Q9UGL1

Pathways: L'effet Warburg