MED1 anticorps (C-Term)

N° du produit ABIN7448659

Cet anticorps Lapin Polyclonal détecte spécifiquement MED1 dans IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour MED1 anticorps (C-Term) (ABIN7448659)

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MED1 anticorps

Épitope: C-Term

Fonction: Rabbit anti-MED1 IHC Antibody, Affinity Purified

Homologie: Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,African elephant,West Indian ocean coelacanth,Gray short-tailed opossum,Small-eared galago,Northern white-cheeked gibbon,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,White-tufted-ear marmoset,Little brown bat,Zebra finch

Purification: Affinity Purified

Immunogène: Between AA 1525 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MED1

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Autre désignation: MED1

Sujet: Background: MED1 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors [taken from the Universal Protein Resource (UniProt) Q15648].

ID gène: 5469

NCBI Accession: NP_004765

UniProt: Q15648

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha