MED15 anticorps (AA 450-500)

N° du produit ABIN7448662

Cet anticorps Lapin Polyclonal détecte spécifiquement MED15 dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour MED15 anticorps (AA 450-500) (ABIN7448662)

Antigène: MED15 (Mediator Complex Subunit 15 (MED15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED15 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MED15 anticorps

Épitope: AA 450-500

Fonction: Rabbit anti-MED15 IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Little brown bat,Small-eared galago,Thirteen-lined ground squirrel,Chinese hamster,Naked mole rat,Ferret,African elephant,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 450 and 500

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MED15

Antigène: MED15 (Mediator Complex Subunit 15 (MED15))

Autre désignation: MED15

Sujet: Background: Mediator complex subunit 15 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. MED15 is required for cholesterol-dependent gene regulation. It also positively regulates the Nodal signaling pathway. [taken from the Universal Protein Resource (UniProt) Q96RN5].

ID gène: 51586

NCBI Accession: NP_001003891

UniProt: Q96RN5

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha