MSH2 anticorps (C-Term)

N° du produit ABIN7448673

Cet anticorps anti-MSH2 est un anticorps Lapin Polyclonal détectant MSH2 dans IHC. Adapté pour Humain et Souris.

Aperçu rapide pour MSH2 anticorps (C-Term) (ABIN7448673)

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSH2 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MSH2 anticorps

Épitope: C-Term

Fonction: Rabbit anti-MSH2 IHC Antibody, Affinity Purified

Homologie: Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Green monkey,Northern white-cheeked gibbon,White-tufted-ear marmoset,Naked mole rat,Ferret,Crab-eating macaque

Purification: Affinity Purified

Immunogène: Between AA 875 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MSH2

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Autre désignation: MSH2

Sujet: Background: MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).

ID gène: 4436

NCBI Accession: NP_000242

UniProt: P43246

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response