HSD17B6 anticorps (AA 61-160)

N° du produit ABIN718556

L’anticorps Lapin Polyclonal anti-HSD17B6 a été validé pour WB, ELISA, FACS, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter HSD17B6 dans des échantillons de Humain.

Aperçu rapide pour HSD17B6 anticorps (AA 61-160) (ABIN718556)

Antigène: HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B6 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HSD17B6 anticorps

Épitope: AA 61-160

Réactivité croisée: Humain

Homologie: Mouse,Rat,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSD17B6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HSD17B6

Antigène: HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

Autre désignation: HSD17B6

Sujet:

Synonyms: 17-beta-HSD 6, 17-beta-HSD6, 17-beta-hydroxysteroid dehydrogenase type 6, 3 hydroxysteroid epimerase, 3alpha >beta hydroxysteroid epimerase, 3alpha >beta hydroxysteroid epimerasel, 3-alpha->beta-HSE, 3-alpha->beta-hydroxysteroid epimerase, H17B6_HUMAN, HSD17B6, HSE, Hydroxysteroid 17 beta dehydrogenase 6, Hydroxysteroid 17 beta dehydrogenase 6 homolog mouse, Hydroxysteroid 17 beta dehydrogenase 6, NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase, NAD+ dependent 3 alpha hydroxysteroid dehydrogenase, Oxidative 3 alpha hydroxysteroid dehydrogenase, Oxidative 3-alpha hydroxysteroid dehydrogenase, Oxidoreductase, Retinol dehydrogenase, RODH, SDR9C6,Short chain dehydrogenase/reductase family 9C, member 6.

Background: NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.Tissue specificity, Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.Sequence similarities, Belongs to the short-chain dehydrogenases/reductases (SDR) family.

ID gène: 8630

Pathways: Steroid Hormone Biosynthesis