UVRAG anticorps (AA 649-699)

N° du produit ABIN7448857

Cet anticorps Lapin Polyclonal détecte spécifiquement UVRAG dans IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour UVRAG anticorps (AA 649-699) (ABIN7448857)

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UVRAG est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-UVRAG anticorps

Épitope: AA 649-699

Fonction: Rabbit anti-UVRAG IHC Antibody, Affinity Purified

Homologie: Rat,Bovine,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Gorilla,Chimpanzee,Chinese hamster,White-tufted-ear marmoset,Northern white-cheeked gibbon,Little brown bat,Naked mole rat,Small-eared galago,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogène: Between AA 649 and 699

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur UVRAG

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Autre désignation: UVRAG

Sujet: Background: UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.

ID gène: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5