NHEJ1 anticorps (AA 200-250)

N° du produit ABIN7448867

L’anticorps Lapin Polyclonal anti-NHEJ1 a été validé pour IHC. Il convient pour détecter NHEJ1 dans des échantillons de Humain.

Aperçu rapide pour NHEJ1 anticorps (AA 200-250) (ABIN7448867)

Antigène: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NHEJ1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-NHEJ1 anticorps

Épitope: AA 200-250

Fonction: Rabbit anti-XLF IHC Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 200 and 250

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NHEJ1

Antigène: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Autre désignation: XLF

Sujet: Background: XRCC4-like factor (XLF) functions in DNA nonhomologous end joining (NHEJ) in double-strand break repair and immune system V(D)J recombination. Mutations of XLF in humans have been documented to result in immunodeficiency, growth retardation, and microcephaly. The yeast of homolog of XLF is Nej1. XLF has been shown to interact with the XRCC4 x DNA-ligase IV complex and is implicated in the DNA religation step of the NHEJ pathway.

ID gène: 79840

NCBI Accession: NP_079058

UniProt: Q9H9Q4

Pathways: Réparation de l'ADN