Recombinant CD68 anticorps

N° du produit ABIN7449045

Cet anticorps anti-CD68 est un anticorps Souris Monoclonal détectant CD68 dans FACS, IHC, IF (p) et mIF. Adapté pour Humain.

Aperçu rapide pour Recombinant CD68 anticorps (ABIN7449045)

Antigène: CD68 (CD68 Molecule (CD68))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD68 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

Clone: KP-1

Détail du produit anti-CD68 anticorps

Fonction: Mouse anti-CD68 Recombinant Monoclonal Antibody, Purified [KP-1]

Purification: Purified

Immunogène: Lysosomal fraction of human lung macrophages

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CD68

Antigène: CD68 (CD68 Molecule (CD68))

Autre désignation: CD68

Sujet: Background: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].

ID gène: 968

NCBI Accession: NP_001242

UniProt: P34810