SMG1 anticorps (AA 1250-1300)

N° du produit ABIN7449171

Cet anticorps anti-SMG1 Polyclonal Lapin (ABIN7449171) détecte spécifiquement SMG1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SMG1 anticorps (AA 1250-1300) (ABIN7449171)

Antigène: SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMG1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SMG1 anticorps

Épitope: AA 1250-1300

Fonction: Rabbit anti-SMG1 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 1250 and 1300

Isotype: IgG

Information d'application

Indications d'application: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SMG1

Antigène: SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))

Autre désignation: SMG1

Sujet: Background: SMG1 is a PIKK (phosphoinositide 3-kinase related kinases) protein kinase that plays a key role in RNA surveillance via nonsense-mediated mRNA decay (NMD). SMG1 phosphorylates Upf1, a factor that possesses RNA helicase activity and is also central to NMD. SMG1 and UPF-1 have been shown to exist in a complex with the translation termination release factors eRF3, and eRF1. This complex has been termed SURF and associates with the exon junction complex (EJC) to function in the recognition of premature termination codons in aberrant RNAs to trigger NMD.

ID gène: 23049

NCBI Accession: NP_055907

UniProt: Q96Q15

Pathways: Inositol Metabolic Process