MCM7 anticorps (AA 300-350)

N° du produit ABIN7449235

Cet anticorps Chèvre Polyclonal détecte spécifiquement MCM7 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour MCM7 anticorps (AA 300-350) (ABIN7449235)

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MCM7 anticorps

Épitope: AA 300-350

Fonction: Goat anti-MCM7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 300 and 350

Isotype: IgG

Information d'application

Indications d'application: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MCM7

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Autre désignation: MCM7

Sujet: Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM7 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity. MCM7 has been shown to interact with CDK4 and p27Kip1 to regulate cell cycle progression. MCM7 has also been shown to interact with ATR-interacting protein (ATRIP)-ATR to function as a transmitter of DNA damage signals from replication forks to S-phase checkpoint machinery.

ID gène: 4176

NCBI Accession: NP_005907

UniProt: P33993

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA