APOE anticorps (HRP)

N° du produit ABIN7449332

L’anticorps Chèvre Polyclonal anti-APOE a été validé pour WB et ELISA. Il convient pour détecter APOE dans des échantillons de Humain.

Aperçu rapide pour APOE anticorps (HRP) (ABIN7449332)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Clone: H10

Détail du produit anti-APOE anticorps (HRP)

Fonction: Goat anti-Human ApoE Antibody HRP Conjugated

Purification: Purified

Immunogène: Human Apolipoprotein E

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:1,000 - 1:8,000

ELISA: 1:1,000 - 1:8,000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.05 % Pro-Clean 400

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: ApoE

Sujet: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

ID gène: 348

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism