Recombinant CD16 anticorps (AA 21-201)

N° du produit ABIN7449423

Cet anticorps anti-CD16 est un anticorps Lapin Monoclonal détectant CD16 dans WB, IHC et ICC. Adapté pour Humain.

Aperçu rapide pour Recombinant CD16 anticorps (AA 21-201) (ABIN7449423)

Antigène: CD16

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD16 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR163J

Détail du produit anti-CD16 anticorps

Épitope: AA 21-201

Fonction: Rabbit anti-CD16 Recombinant Monoclonal Antibody [BLR163J]

Immunogène: residues 21-201 (ECD)

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CD16

Antigène: CD16

Autre désignation: CD16

Sujet: Background: CD16A (FCGR3A) is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. CD16A is highly similar to another nearby gene (CD16B, FCGR3B) located on chromosome 1. CD16A is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas CD16B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. [taken from NCBI Entrez Gene (Gene ID: 2214)].

ID gène: 2214, 2215

NCBI Accession: NP_000560

UniProt: P08637, O75015

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process