Prohibitin 2 anticorps (C-Term)

N° du produit ABIN7449571

Cet anticorps Lapin Polyclonal détecte spécifiquement Prohibitin 2 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Prohibitin 2 anticorps (C-Term) (ABIN7449571)

Antigène: Prohibitin 2 (PHB2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Prohibitin 2 anticorps

Épitope: C-Term

Fonction: Rabbit anti-REA Antibody, Affinity Purified

Homologie: Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: between AA 250 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 1 - 4 μg/mg lysate

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: REA

Sujet: Background: REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.

ID gène: 11331

NCBI Accession: NP_009204

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling