ube3a anticorps (AA 75-125)
Aperçu rapide pour ube3a anticorps (AA 75-125) (ABIN7449574)
Antigène
Voir toutes ube3a AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 75-125
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Fonction
- Rabbit anti-E6AP Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 75 and 125
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Isotype
- IgG
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Indications d'application
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IP: 1 - 4 μg/mg lysate
WB: 1:1,000 - 1:5,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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Autre désignation
- E6AP
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Sujet
- Background: E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.
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ID gène
- 7337
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NCBI Accession
- NP_000453
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UniProt
- Q05086
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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